Leading Medical Apps by Monthly Active Users in the USA 2025

The healthcare landscape is undergoing a technological revolution, and medical apps are at the forefront of this transformation. By 2025, the demand for medical apps has skyrocketed, driven by an increased focus on remote healthcare, health management, and personalized wellness. Below, we explore the leading medical apps in the USA based on their monthly active users (MAUs).

1. MyChart

Monthly Active Users: Over 50 million

MyChart, developed by Epic Systems, remains a leading medical app in the USA. It provides patients with a comprehensive platform to manage their health records, book appointments, and communicate with healthcare providers. In 2025, MyChart's seamless integration with wearable devices and its advanced AI-driven digital healthcare solutions  insights have contributed to its growing popularity.

Key Features:

• Access to personal health records

• Secure messaging with providers

• Prescription refill requests

• Integration with wearable health trackers

Why It’s Popular: MyChart’s ability to consolidate medical records from multiple providers into a single platform has made it indispensable for millions of Americans.

2. Teladoc Health

Monthly Active Users: Approximately 35 million

As the leader in telemedicine, Teladoc Health offers virtual consultations with licensed doctors, therapists, and other healthcare professionals. Its growth in 2025 is fueled by the rising adoption of telehealth services, especially in rural areas where access to healthcare can be challenging.

Key Features:

• 24/7 access to virtual healthcare

• Mental health counseling

• Chronic condition management

• Integration with health insurance plans

Why It’s Popular: Teladoc Health’s commitment to providing affordable and accessible healthcare has solidified its place as a go-to platform for millions of users.

3. Fitbit

Monthly Active Users: Over 30 million

Fitbit, now a part of Google, continues to dominate the fitness and wellness app segment. While it started as a fitness tracker, Fitbit has expanded into a holistic health app, offering features like sleep monitoring, heart rate tracking, and stress management tools. By 2025, its partnership with healthcare providers to deliver personalized health insights has made it a favorite among users.

Key Features:

• Real-time activity and health tracking

• Personalized fitness goals

• Sleep and stress management tools

• Integration with Google Health

Why It’s Popular: Nexa Core Digital, coupled with its ability to integrate fitness data into broader health management systems, have kept users engaged.

4. GoodRx

Monthly Active Users: Around 25 million

GoodRx helps users find the best prices for prescription medications and offers discounts at pharmacies nationwide. As medication costs continue to rise, GoodRx has become an essential tool for Americans looking to save money on their prescriptions.

Key Features:

• Price comparisons for medications

• Printable and digital coupons

• Telehealth services

• Pill reminder tools

Why It’s Popular: GoodRx’s ability to provide significant cost savings on prescriptions has driven its widespread adoption.

5. Headspace

Monthly Active Users: 20 million

Mental health and wellness apps have gained immense traction, and Headspace is leading the pack. Known for its guided meditation sessions, Headspace has expanded its offerings to include stress management, sleep support, and mental health resources in 2025.

Key Features:

• Guided meditation and mindfulness exercises

• Sleepcasts and relaxation tools

• Stress and anxiety management programs

• Partnerships with employers for mental health support

Why It’s Popular: The growing awareness of mental health has made Headspace a crucial app for individuals looking to improve their well-being.

6. Peloton

Monthly Active Users: 18 million

Peloton’s app, known for its immersive fitness classes, has become a staple for fitness enthusiasts in the USA. In 2025, the app offers a wide range of workout categories, including strength training, yoga, and cardio, catering to users with or without Peloton equipment.

Key Features:

• Live and on-demand fitness classes

• Personalized training programs

• Community challenges and leaderboards

• Offline access to workouts

Why It’s Popular: Peloton’s engaging and interactive fitness ecosystem keeps users motivated and connected.

7. BetterHelp

Monthly Active Users: 15 million

BetterHelp has emerged as a leading platform for online therapy in 2025. The app connects users with licensed therapists, offering flexible and affordable mental health support.

Key Features:

• Secure messaging with therapists

• Video and phone therapy sessions

• Flexible pricing plans

• Specialized therapy programs (e.g., couples therapy, teen counseling)

Why It’s Popular: BetterHelp’s accessibility and affordability make professional mental health care available to a broader audience.

8. MyFitnessPal

Monthly Active Users: 14 million

MyFitnessPal remains a top app for diet and nutrition tracking. By 2025, its database of over 14 million foods, combined with AI-driven insights, has made it an indispensable tool for those looking to improve their dietary habits.

Key Features:

• Calorie and nutrient tracking

• Meal planning and recipes

• Integration with fitness trackers

• Community support and challenges

Why It’s Popular: The app’s user-friendly interface and extensive food database have earned it a loyal user base.

9. Medscape

Monthly Active Users: 10 million

Medscape is a trusted resource for healthcare professionals and medical students. By 2025, the app’s wealth of clinical resources, drug information, and continuing education opportunities have made it indispensable in the medical community.

Key Features:

• Drug interaction checkers

• Medical news and research updates

• Continuing medical education (CME) courses

• Clinical calculators and tools

Why It’s Popular: Medscape’s reliable and up-to-date content has cemented its position as a leading medical resource.

10. Zocdoc

Monthly Active Users: 8 million

Zocdoc simplifies the process of finding and booking healthcare appointments. By 2025, its ability to provide verified patient reviews and real-time appointment availability has made it a trusted app for many Americans.

Key Features:

• Online appointment booking

• Verified patient reviews

• Insurance compatibility checks

• Telehealth options

Why It’s Popular: Zocdoc’s convenience and transparency in connecting patients with healthcare providers make it a valuable tool.

Conclusion

As of 2025, medical apps in the USA are playing a critical role in empowering users to take control of their health and well-being. From managing chronic conditions to improving mental health, these apps offer innovative solutions that cater to diverse healthcare needs. As technology continues to evolve, the potential for these apps to transform the healthcare industry is limitless. With their growing user bases, these leading medical apps are not just tools but essential companions in the journey toward better health.